The next step of BIOTOUCH is to continue our open innovation and collaboration. Macarena Pallares did a great work to get this blog started. She returns to Mexico but I think it's a good idea to to keep this blog alive. I noticed that Juha posted a new post to mark the continuation of the dialog.
At the end of last month we had an interesting distributed discussion with a student from Jaipur India. Below is the content of that discussion. It would be nice to see that also this dialog continues.
At the same time we can think about tactical means of using a social media and blogs to boost lead generation. We would like to see more people participating. Biotouch is still looking for investors and partners who want to take a serious move towards the bio-based economy.
But let's get to the Indian-Finnish biofuel discussion.
Here is how it all started. You can follow how the questions and answers criss-crossed and at this point we can see the starting point of Rajesh's project.
I'd like to invite more people to participate in this cross-border learning process.
We've a case in India but there are certainly hundreds of new initiated projects around the globe. How could we join forces and get more people involved?
The biggest challenge is to get the investors to move into this space.
Rajesh Kumar Sharma
"Sir, I'm a student of B.Tech-M.Tech Int. prgramme in converging technologies at UNIVERSITY OF RAJASTHAN, Jaipur, India. I have to make a project for a scholarship programme for which i need your help. My idea is to take ATP's from algae and use the energy derived from it to run a vehicle or some other process. It will be a pollution free and cost effective fuel(I think so).But the problem is that I don't know how can this be done. So I wan't to know that how can we take out ATP's from it. Please help me in making this project and give me advise regarding how should I proceed for this project."
Thank you!
Yours Sincerely,
Rajesh Kumar Sharma
rks.9690 at gmail.com
Date: 2008/7/31
From: Helge V. Keitel
To: Rajesh Kumar Sharma,
Rajesh Kumar Sharma,
I sent a copy of your email to the microbiologist Juha Veikko Mentu and to biotechnologist Elias Hakalehto.
Also take a look at these blogs:
- http://industrymicrobiologist.blogspot.com/
- http://biotechtouch.blogspot.com/
- http://smartroad.blogspot.com/
Juha Veikko Mentu's Pulp, Paper, Board and Packaging Microbiologist blog statement:
"This blog contains novel ideas for the development of paper industry microbiology. Traditional methods, despite their important role in the selection of harmful microbes from process and product samples, does not fulfil the needs of modern HACCP and process stability control. Faults in the process management as well as in the QC of products can cause hazardous situations for the economy of production as well as for the safety of employers, customers and environment."
Dear Rajesh Kumar Sharma;
I am very pleased to hear about your interest in ATP.
I have performed practical experiences with ATP. Luminometric ATP assay has been most important tool for the estimation of bacterial loads in paper industry processes since late 80's for me, too. In addition, I know two researchers in Jyväskylä, Finland, who have performed basic research of ATP biochemistry.
ATP is defenitely a biochemical "battery" in all living cells. If the high-energy bond between phosphate groups will be opened, active phosphate group will thereafter give energy for several biochemical reactions.
I have two questions concerning your idea:
- how to transform this biochemical energy into other, practical forms of energy?
- how to avoid the breakdown of ATP (by temperature, ATPase etc.)?
Your idea, however, is very interesting, and I am looking forward to hear more about it. I will also give my (relatively humble) knowledge of ATP to you when needed.
- I have participated a project at the end of 70's where the usage of cyanobacteria as fertilizers was the subject of the study. I learned a lot about the beneficial effects of these organisms on rice fields of India - as an example, their ability to fix atmospheric nitrogen.
With best regards,
Juha Mentu
--
Juha Mentu
Environmental and paper industry microbiologist
juha.veikko.mentu at gmail.com
http://industrymicrobiologist.blogspot.com
tel: +358(0)468973426
From: Elias Hakalehto
To: Juha, rajesh, Helge, Macarena
Date: Jul 31, 2008
Subject: Reply
Dear Rajesh,
Greetings from Kuopio, Finland! I think that you are having some clue in this reasoning. Nature provides us with an excellent machinery to be fuelled with ATP - the cell metabolism.
The chemical energy in the form of ATP is most important power source of the cells on the molecular level as we know.- However, there is a point in thinking how to get the ATP to work the best. In bacterial cells the catabolic pathways will often end up with exploitable chemical substances like ethanol, butanol, or organic acids. They are containing in a way the "ATP energy" in them, and are exploitable as such.
One way to continue our mental excercise is to reason where the ATP is generated in the cells and where it is functional = is delivering its energy content to another chemical compounds. In this way we can at least try to deduce which is the most energy effective solution for the cell, and try to check if it is actually working accordingly.
To isolate and use ATP in a functional form is then another thing as Juha wrote. For that to be effective we have to make "the vehicle" that you had mentioned. We will come to that later.
Thank you very much for taking up this inspiring topic.
With best regards,
Elias Hakalehto, PhD, MSc(Agr.Sci)
Microbiologist, Biotechnologist
Docent in Biotechnical Microbe Analytics
Internat.Postgrad.Diploma in Biotechnology
+358-500-574 289
elias.hakalehto at gmail.com
www.finnoflag.com
From: Helge V. Keitel
To: Elias, Juha, rajesh, Macarena
Subject: Reply to all
Hello everybody,
This collaboration shows the power of open social networking on a global scale. Rajesh, it would be interesting to expand this discussion with the teachers/professors and to have a continuous dialog about your work. Would it be possible to exchange some kinds of progress reports?
A continuous dialog would show us the power open innovation and the use of social media to advance global collaboration.
I think that the society at large is still quite clueless about how we should proceed on the bumpy road towards a less oil dependent and towards a bio-based economy.
Dr. Elias Hakalehto at Finnoflag Oy, Finland, has been thinking about ways to get industrialists, innovators, the research community, and financiers to collaborate around themes leading to cost-effective biorefineries, but there is still a lot of work to be done to get down to soundly financed projects.
So, let's continue the talk. We never know what "The Wisdom of the Crowd" can bring to the table.
Rajesh, I wish you success with your project and keep us informed.
Br
Helge
Terveisin, Best Regards, Med Vanliga Halsningar, Mit Freundlichen Grüßen, A Bientot,
Helge V. Keitel
KK-Net
Kuningattarenkatu 13 B, 07900 Loviisa, Finland
Skype: visualradio
Phone: + 358 50 309 2021
Home: http://wwww.kknet.fi
Business Development: http://digitalvillages.net/
Blog: http://digitalvillages.blogspot.com
Wiki: http://www.digitalvillages.net/global.htm
Email: helgekeitel at gmail.com
Social Collaboration & Virtual Organizations | Open Innovation & Global Networking | Biotech, Biotouch, Bioenergy and Health Care
8 comments:
Dear Rajesh and partners in BIOTOUCH!
I have been thinking about this novel idea to transfer the energy of ATP into other forms outside the cells.
The system for controlling transformations of ATP into "activated phosphate" and ADP (and vice versa) is relatively complicated, containing several enzymes. A microbial cell is "a factory" where the biochemical reactions are interconnected and regulated.
If your idea does not include "traditional" biotechnology (where the microbial cells do the work, either to produce some organic compound or biomass), I see the usage of complex ATP system outside the cells in a similar manner which is known in the area of enzymes.
The main problem still stays: how to transform energy, which is intended into acceleration of biochemical reactions, into useful form for human beings?
Still, this idea is a most fascinating one. I am waiting to hear about your progress!
With best regards,
Juha ("Industrymicrobiologist").
Juha, Wow, sounds great what you're writing.
I think it's a progress that we've been able to take the close Basecamp discussion "out to the open."
There is still a long way to go before we get "this novel idea to transfer the energy of ATP into other forms outside the cells."
I'm curious about where this new open discussion is taking us.
I know that you and Elias have a lot to bring to this discussion. I'd also like to see more people participating.
Br
Helge
Dear Rajesh and partners in BIOTOUCH!
ATP is mainly regenerated from ADP by tricarboxylic acid cycle. If delivered outside the cell, it very easily breaks down.
Coud you image that everything actually happens inside the algae cells? Could we modify the routes of ATP metabolism to have something which could be used as energy source? There already is one manipulation of tricarboxylic acid cycle where one enzymatic reaction is inhibited and the organic acid before this step is continuously concentrating.
Something similar to produce some fuel inside a cell...a most fascinating idea.
Regards,
Juha
Dear Juha, and everyone else too,
I was just pondering the idea of running engines on ATP when i stumbled across this site, its cool that you've already had the same idea as me!
I was wondering if it would be possible to have a transparant plastic container near the engine (perhaps across the top of the wing if we were talking planes) with a connection to the engine where the fuel is normally injected.
inject concentrated ATP from the algae instead of say gasoline or petrol, shut off the connection, and ignite. Heat would stimulte the exothermic ATP -> ADP + H+ reaction, and the mini explosion would move the piston. Repeat process in the usual way for an engine.
I recon this should first be tested in a model engine, which are apparantly quite cheap at not too much more that £10.
Where are you in your thoughts/plans now?
I would love to try this out!! Lets team up!!
Dear Juha, and everyone else too,
I was just pondering the idea of running engines on ATP when i stumbled across this site, its cool that you've already had the same idea as me!
I was wondering if it would be possible to have a transparant plastic container near the engine (perhaps across the top of the wing if we were talking planes) with a connection to the engine where the fuel is normally injected.
inject concentrated ATP from the algae instead of say gasoline or petrol, shut off the connection, and ignite. Heat would stimulte the exothermic ATP -> ADP + H+ reaction, and the mini explosion would move the piston. Repeat process in the usual way for an engine.
I recon this should first be tested in a model engine, which are apparantly quite cheap at not much more that £10.
Where are you in your thoughts/plans now?
I would love to try this out!! Lets team up!!
Dear Helge Sir, Juha Sir and others on BIOTOUCH!
Greetings from India!
I'm both happy and sad while writing this comment. I'm happy that today I'm back with an advancement on this page where one of my original ideas has been discussed by learned, open and innovative people. I'm sad because it took a huge amount of time for me to come back here.
I want to bring to your kind notice that I did some extensive study of research articles and books to develop this idea.
It has been repeatedly posted by Juha Sir that how the energy extracted can be transformed into other forms of energy? I have come up with some novel schematics based on past research and innovative ideation which are promising and vital for this idea. My schematics incorporate nanotechnology and nanomaterials tools as well as bionanotechnology, bioelectronics and biosensor technology. There are ways in which we can do it. I'm trying to contact Professors who are working in related fields to do some experimental work. As soon as I get experimental results, I will share them with you.
I would like to hear from you if you have progressed on this idea.
Thank you!
Sincere Regards,
Rajesh Kumar Sharma
B.Tech.-M.Tech Integrated Nanotechnology and Nanomaterials
Centre for Converging Technologies,
University of Rajasthan,
Jaipur, Rajasthan, India
Dear Raje, thanks a lot for your comment. We're working with Juha Mentu to activate Biotechtouch blogging and also looking at some business opportunities in India. We'll be able to tell some details after the summer season.
Br
Helge
Good blog ppost
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