Monday, August 4, 2008

Biotouch discussing ATP's from algae and energy derived from it

I want to share the exchange of email postings with you. It crossed my mind that we could talk about technical and biotech stuff like we follow soap operas. The power of social media is better demonstrated if we follow a continuous process, the evolution of things, how a project started, etc. Now we are at the very beginning...

The next step of BIOTOUCH is to continue our open innovation and collaboration. Macarena Pallares did a great work to get this blog started. She returns to Mexico but I think it's a good idea to to keep this blog alive. I noticed that Juha posted a new post to mark the continuation of the dialog.

At the end of last month we had an interesting distributed discussion with a student from Jaipur India. Below is the content of that discussion. It would be nice to see that also this dialog continues.

At the same time we can think about tactical means of using a social media and blogs to boost lead generation. We would like to see more people participating. Biotouch is still looking for investors and partners who want to take a serious move towards the bio-based economy.

But let's get to the Indian-Finnish biofuel discussion.

Here is how it all started. You can follow how the questions and answers criss-crossed and at this point we can see the starting point of Rajesh's project.

I'd like to invite more people to participate in this cross-border learning process.

We've a case in India but there are certainly hundreds of new initiated projects around the globe. How could we join forces and get more people involved?

The biggest challenge is to get the investors to move into this space.

Rajesh Kumar Sharma

"Sir, I'm a student of B.Tech-M.Tech Int. prgramme in converging technologies at UNIVERSITY OF RAJASTHAN, Jaipur, India. I have to make a project for a scholarship programme for which i need your help. My idea is to take ATP's from algae and use the energy derived from it to run a vehicle or some other process. It will be a pollution free and cost effective fuel(I think so).But the problem is that I don't know how can this be done. So I wan't to know that how can we take out ATP's from it. Please help me in making this project and give me advise regarding how should I proceed for this project."

Thank you!

Yours Sincerely,
Rajesh Kumar Sharma
rks.9690 at

Date: 2008/7/31
From: Helge V. Keitel
To: Rajesh Kumar Sharma,

Rajesh Kumar Sharma,

I sent a copy of your email to the microbiologist Juha Veikko Mentu and to biotechnologist Elias Hakalehto.

Also take a look at these blogs:

Juha Veikko Mentu's Pulp, Paper, Board and Packaging Microbiologist blog statement:

"This blog contains novel ideas for the development of paper industry microbiology. Traditional methods, despite their important role in the selection of harmful microbes from process and product samples, does not fulfil the needs of modern HACCP and process stability control. Faults in the process management as well as in the QC of products can cause hazardous situations for the economy of production as well as for the safety of employers, customers and environment."

Dear Rajesh Kumar Sharma;

I am very pleased to hear about your interest in ATP.

I have performed practical experiences with ATP. Luminometric ATP assay has been most important tool for the estimation of bacterial loads in paper industry processes since late 80's for me, too. In addition, I know two researchers in Jyväskylä, Finland, who have performed basic research of ATP biochemistry.

ATP is defenitely a biochemical "battery" in all living cells. If the high-energy bond between phosphate groups will be opened, active phosphate group will thereafter give energy for several biochemical reactions.

I have two questions concerning your idea:

- how to transform this biochemical energy into other, practical forms of energy?
- how to avoid the breakdown of ATP (by temperature, ATPase etc.)?

Your idea, however, is very interesting, and I am looking forward to hear more about it. I will also give my (relatively humble) knowledge of ATP to you when needed.

- I have participated a project at the end of 70's where the usage of cyanobacteria as fertilizers was the subject of the study. I learned a lot about the beneficial effects of these organisms on rice fields of India - as an example, their ability to fix atmospheric nitrogen.

With best regards,
Juha Mentu
Juha Mentu
Environmental and paper industry microbiologist
juha.veikko.mentu at
tel: +358(0)468973426

From: Elias Hakalehto
To: Juha, rajesh, Helge, Macarena
Date: Jul 31, 2008
Subject: Reply

Dear Rajesh,

Greetings from Kuopio, Finland! I think that you are having some clue in this reasoning. Nature provides us with an excellent machinery to be fuelled with ATP - the cell metabolism.

The chemical energy in the form of ATP is most important power source of the cells on the molecular level as we know.- However, there is a point in thinking how to get the ATP to work the best. In bacterial cells the catabolic pathways will often end up with exploitable chemical substances like ethanol, butanol, or organic acids. They are containing in a way the "ATP energy" in them, and are exploitable as such.

One way to continue our mental excercise is to reason where the ATP is generated in the cells and where it is functional = is delivering its energy content to another chemical compounds. In this way we can at least try to deduce which is the most energy effective solution for the cell, and try to check if it is actually working accordingly.

To isolate and use ATP in a functional form is then another thing as Juha wrote. For that to be effective we have to make "the vehicle" that you had mentioned. We will come to that later.

Thank you very much for taking up this inspiring topic.

With best regards,

Elias Hakalehto, PhD, MSc(Agr.Sci)
Microbiologist, Biotechnologist
Docent in Biotechnical Microbe Analytics
Internat.Postgrad.Diploma in Biotechnology
+358-500-574 289
elias.hakalehto at

From: Helge V. Keitel
To: Elias, Juha, rajesh, Macarena
Subject: Reply to all

Hello everybody,

This collaboration shows the power of open social networking on a global scale. Rajesh, it would be interesting to expand this discussion with the teachers/professors and to have a continuous dialog about your work. Would it be possible to exchange some kinds of progress reports?

A continuous dialog would show us the power open innovation and the use of social media to advance global collaboration.

I think that the society at large is still quite clueless about how we should proceed on the bumpy road towards a less oil dependent and towards a bio-based economy.

Dr. Elias Hakalehto at Finnoflag Oy, Finland, has been thinking about ways to get industrialists, innovators, the research community, and financiers to collaborate around themes leading to cost-effective biorefineries, but there is still a lot of work to be done to get down to soundly financed projects.

So, let's continue the talk. We never know what "The Wisdom of the Crowd" can bring to the table.

Rajesh, I wish you success with your project and keep us informed.


Terveisin, Best Regards, Med Vanliga Halsningar, Mit Freundlichen Grüßen, A Bientot,

Helge V. Keitel
Kuningattarenkatu 13 B, 07900 Loviisa, Finland
Skype: visualradio

Phone: + 358 50 309 2021
Business Development:
Email: helgekeitel at

Social Collaboration & Virtual Organizations | Open Innovation & Global Networking | Biotech, Biotouch, Bioenergy and Health Care
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